A 2017 literature review, published in Cannabis and Cannabinoid Research by Mary Ann Liebert Inc., examined the use of cannabis for headache disorders in general.
Researchers concluded that, in tandem with more clinical trials, cannabis will likely emerge as a treatment option for some headache sufferers.
Identifying the unique benefits of oral cannabinoids as a preventative treatment for headaches, researchers also pinpointed CBD as a treatment for headache-related conditions, including anxiety.
A more recent literature review, published in 2018 in Frontiers in Pharmacology, concluded that cannabinoids are a promising class of compounds for preventing and treating migraines.
Cannabinoid receptors in the brain can also be targeted to reduce inflammation associated with severe migraines, according to researchers.
These current research suggests that cannabis medicine could be an effective treatment for migraines, and future studies could propel medical marijuana beyond alternative treatment status.